The effect of WR 149024 on survival following hemorrhage in conscious rats.
نویسندگان
چکیده
The effect of WR 149024, an alpha-receptor antagonist, on survival following hemorrhage with no volume replacement therapy, was investigated. WR 149024 (either 5.0 or 50.0 mg/kg) was administered intraperitoneally (i.p.) to conscious rats during exsanguination. Both WR 149024 treatments caused a significant decrease in survival (P less than 0.021), compared with water-injected controls.
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ورودعنوان ژورنال:
- Toxicology letters
دوره 26 2-3 شماره
صفحات -
تاریخ انتشار 1985